Cardiac Spinal Afferents: Role of H1 Receptors and PKC Histamine Contributes to Ischemia-Related Activation of
نویسندگان
چکیده
منابع مشابه
Histamine contributes to ischemia-related activation of cardiac spinal afferents: role of H1 receptors and PKC.
Myocardial ischemia activates cardiac spinal afferents that transmit the nociceptive information leading to chest pain and elicit excitatory cardiovascular reflexes. Previous studies have shown that histamine is increased in coronary sinus blood during myocardial ischemia and that this autacoid stimulates abdominal visceral afferents. The present investigation evaluated the role of endogenous h...
متن کاملEndogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.
Abdominal ischemia stimulates sympathetic visceral afferents to reflexly activate the cardiovascular system. We have shown previously that topical application of histamine (HA) to the gastric wall causes reflex cardiovascular responses and have documented increased histamine concentrations in intestinal lymph and portal venous plasma during brief abdominal ischemia. In the present study, we hyp...
متن کاملThe role of central endogenous histamine and H1, H2 and H3 receptors on food intake in broiler chickens
The role of endogenous histamine and H1, H2 and H3 central receptors on food intake in broiler chickenswas investigated. For this purpose, a probe was used to manipulate the concentration of endogenoushistamine by intracerebroventricular (ICV) injection of thioperamide, an H3 receptor antagonist, and R-α-methylhistamine, an H3 receptor agonist and subsequently the effects of brain histaminergic...
متن کاملAntinociceptive effect of the aqueous extract obtained from Foeniculum vulgare in mice: the role of histamine H1 and H2 receptors
Foeniculum vulgare (fennel) has been widely used in traditional medicine for treatment of variousdiseases including pediatric colic. This study was designed to assess the antinociceptive effects of aqueousextract of F. vulgare on visceral pain and possible involvement of opioidergic, serotonergic, adrenergic andhistaminergic systems. The results of this study showed that aqueous extract of F. v...
متن کاملInteractions between Histamine H1 and H3 and Dopamine D1 Receptors on feeding behavior in chicken
BACKGROUND: Brain monoamines (such as histamine and dopamine) play an important role in emotions, cognition, reward and feeding behavior. The interactions between histamine and dopamine were studied in many physiological functions but this correlation is unclear in feeding behavior of chickens. The aim of this study was to investigate the interaction of central histaminergic and dopaminergic sy...
متن کامل